Detalles de la búsqueda
1.
Combinatorial targeting of G-protein-coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug-induced liver injury.
Hepatology;
78(1): 26-44, 2023 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36107019
2.
Atorvastatin protects against liver and vascular damage in a model of diet induced steatohepatitis by resetting FXR and GPBAR1 signaling.
FASEB J;
36(1): e22060, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34862975
3.
Theonella: A Treasure Trove of Structurally Unique and Biologically Active Sterols.
Mar Drugs;
21(5)2023 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37233485
4.
Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists.
Molecules;
28(6)2023 Mar 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36985811
5.
The bile acid activated receptors GPBAR1 and FXR exert antagonistic effects on autophagy.
FASEB J;
35(1): e21271, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33368684
6.
Discovery of Bile Acid Derivatives as Potent ACE2 Activators by Virtual Screening and Essential Dynamics.
J Chem Inf Model;
62(1): 196-209, 2022 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34914393
7.
The Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver Toxicity.
J Immunol;
204(9): 2535-2551, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32213564
8.
Discovering New G-Quadruplex DNA Catalysts in Enantioselective Sulfoxidation Reaction.
Int J Mol Sci;
23(3)2022 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35163018
9.
Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR).
Bioorg Chem;
111: 104897, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33901797
10.
Characterisation of the Dynamic Interactions between Complex N-Glycans and Human CD22.
Chembiochem;
21(1-2): 129-140, 2020 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31095840
11.
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.
FASEB J;
33(2): 2809-2822, 2019 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-30303744
12.
The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.
J Immunol;
199(2): 718-733, 2017 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28607110
13.
Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists.
Handb Exp Pharmacol;
256: 137-165, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31201554
14.
Introduction of Nonacidic Side Chains on 6-Ethylcholane Scaffolds in the Identification of Potent Bile Acid Receptor Agonists with Improved Pharmacokinetic Properties.
Molecules;
24(6)2019 Mar 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-30884797
15.
Disruption of TFGß-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.
Pharmacol Res;
131: 17-31, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29530598
16.
Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: role of gaseous mediators.
Am J Physiol Heart Circ Physiol;
312(1): H21-H32, 2017 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27765751
17.
Determination of Gymnemic Acid I as a Protein Biosynthesis Inhibitor Using Chemical Proteomics.
J Nat Prod;
80(4): 909-915, 2017 04 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28256837
18.
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.
Am J Physiol Heart Circ Physiol;
309(1): H114-26, 2015 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25934094
19.
Marine and semi-synthetic hydroxysteroids as new scaffolds for pregnane X receptor modulation.
Mar Drugs;
12(6): 3091-115, 2014 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24871460
20.
Bioactive cembrane derivatives from the Indian Ocean soft coral, Sinularia kavarattiensis.
Mar Drugs;
12(7): 4045-68, 2014 Jul 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25056629